Domain structure of the unrearranged PML protein and P/R fusion proteins. Note the same RBCC domain (e.g., RING finger, B-box, and coiled-coil) in the N-terminus but different in the C-terminus.

RA controls fundamental developmental processes, induces terminal differentiation of myeloid haemopoietic progenitors, and suppresses tumour and cell growth 1,2. RA receptors (RARs) are nuclear ...

Coiled coils are extensively and successfully used nowadays to rationally design multistranded structures for applications, including basic research, biotechnology, nanotechnology, materials science, ...

The biological functions of coiled coils generally depend on efficient folding and perfect pairing of their α-helices. Dynamic changes in the helical registry that lead to staggered helices have only ...