The Remnant 2 Void Heart Relic can only be collected if you complete the N’Erud story quest involving Seeker Keys and the Sha’Hala world boss. Using this Relic gives you 50% damage resistance ...

The Void Heart is a powerful relic that you can equip in Remnant 2. When activated, it gives you a significant damage reduction buff for four seconds before finally healing all of your missing Health.