'Molecular glue' stabilizes protein that inhibits development of non-small cell lung cancer

Lung cancer is the second-most common cancer and the leading cause of cancer death in the United States. Over 80% of lung ...

Structure Therapeutics Reports Positive Topline Data from ACCESS Program for its Once-Daily Oral Small Molecule GLP-1 Receptor Agonist, Aleniglipron

Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for metabolic diseases, with a focus on obesity, today ...
New Scientist

A sinister, deadly brain protein could reveal the origins of all life

In 1944, Erwin Schrödinger published a book called What Is Life?. The physicist, famous for his alive-and-dead cat, clearly relished a brainteaser. Today, there is still no good definition. Life is ...
Frontiers

Funnel-shaped fluid-escape structure: a clastic dyke complex formed by multiple, discrete fluidizations

1 Department of Geological Science, University of Science and Technology, Daejeon, Republic of Korea 2 Petroleum and Future Energy Research Center, Resource Exploration and Development Research ...
IEEE

Characterizing Secretion System Effector Proteins With Structure-Aware Graph Neural Networks and Pre-Trained Language Models

Abstract: The Type III Secretion Systems (T3SSs) play a pivotal role in host-pathogen interactions by mediating the secretion of type III secretion system effectors (T3SEs) into host cells. These ...