Rolling Out1d
Failed ALS trials reveal major medical breakthrough
Innovative platform trial revolutionizes ALS research by testing multiple treatments simultaneously, offering new hope ...
Medscape3d
ALS Trials Fail to Meet Key Endpoints…But It’s Still a Win and Here’s Why
While main results from a platform study of four experimental drugs for amyotrophic lateral sclerosis are negative, it shows ...
emjreviews.com4d
HEALEY Trial: Pridopidine Fails to Slow ALS Progression
NEW research has shown that pridopidine, a sigma-1 receptor agonist, does not exhibit a significant impact on the progression of amyotrophic lateral sclerosis (ALS) over a 24-week period.
manilatimes2d
Clene and APST Enter Into an Agreement to Support FDA's Recommendation for Long-Term NfL Biomarker Analyses of CNM-Au8®'s Impact on NfL Reduction
Longitudinal ALS patient data from APST Research will enable a more robust analysis of the effect of CNM-Au8 on NfL biomarkers; APST Research data includes thousands of people liv ...
The Bakersfield Californian2d
Clene and APST Enter Into an Agreement to Support FDA’s Recommendation for Long-Term NfL ...
Longitudinal ALS patient data from APST Research will enable a more robust analysis of the effect of CNM-Au8 on NfL biomarkersAPST Research data includes thousands of people living with ALS ...
pharmaphorum1d
Four more drugs in keenly watched ALS trial miss the mark
Four more experimental drugs for amyotrophic lateral sclerosis (ALS) have failed to hit the primary endpoint in the phase 2/3 HEALEY ALS basket trial, which is trying to accelerate the search for ...
Daily6d
Verdiperstat use may not impact progression of amyotrophic lateral sclerosis: JAMA
A new study published in the recent issue of Journal of American Medical Association found that the usage of verdiperstat, a ...
ALS News Today21m
New analyses in ALS planned to aid CNM-Au8’s accelerated approval
Clene will join APST Research to explore how CNM-Au8 affects NfL levels in ALS patients treated in expanded access programs.
ALS News Today6d
Results published for first 4 drugs in HEALEY trial; 2 to be tested further
Of the first four experimental ALS treatments tested in the HEALEY platform trial, CNM-Au8 and pridopridine showed some ...
pharmaphorum5d
Denali slides after ALS drug flunks clinical test
Denali Therapeutics' experimental drug for amyotrophic lateral sclerosis (ALS) failed to show efficacy in part of the phase 2/3 HEALEY ALS basket trial, causing a fall in its share price.
Yahoo Finance2d
Clene Inc. (CLNN)
FDA recommends that Clene leverage additional Neurofilament Light (NfL) data from its three Expanded Access Protocols (EAPs) and the HEALEY ALS Platform Trial to support earlier presented ...