thorax.bmj18h
Lung cancer • 4: Chemotherapy for non-small cell lung cancer: the end of the beginning
The development of chemotherapy for NSCLC over the last 20 years is reviewed, particularly with regard to its palliative effects. New “fourth generation” agents designed to inhibit specific biological ...
thorax.bmj18h
Influence of atmospheric nitric oxide concentration on the measurement of nitric oxide in exhaled air
BACKGROUND Measurement of nitric oxide (NO) in exhaled air shows promise as a non-invasive method of detecting lung inflammation. However, variable concentrations of NO are measured in environmental ...
thorax.bmj4d
Incidence and characteristics of viral community-acquired pneumonia in adults
Background: In adults, viral causes of community-acquired pneumonia (CAP) are poorly characterised. The aims of this study were to characterise the viral aetiology of CAP in adults by using an ...
thorax.bmj3d
Effect of diet on asthma and allergic sensitisation in the International Study on Allergies and Asthma in Childhood (ISAAC) Phase Two
2 Pediatric Respiratory and Allergy Units, “Arrixaca” University Children's Hospital, University of Murcia and CIBER of Epidemiology and Public Health (CIBERSP), Murcia, Spain 3 Division of Community ...
thorax.bmj13d
Exhaled nitric oxide measurements: clinical application and interpretation
1 Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, P O Box 913, Dunedin, New Zealand 2 Department of Paediatric Respiratory Medicine, Erasmus MC - Sophia ...
thorax.bmj2d
Airflow obstruction in bronchiectasis: correlation between computed tomography features and pulmonary function tests
BACKGROUND An obstructive defect is usual in bronchiectasis, but the pathophysiological basis of airflow obstruction remains uncertain. High resolution computed tomographic (CT) scanning now allows ...
thorax.bmj9d
Gene expression networks in COPD: microRNA and mRNA regulation
1 Department of Medicine, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Columbus, Ohio, USA Background The mechanisms underlying chronic obstructive ...
thorax.bmj4d
The 6 minute walk in idiopathic pulmonary fibrosis: longitudinal changes and minimum important difference
1 Interstitial Lung Disease Program and Autoimmune Lung Center, National Jewish Health, Denver, Colorado, USA 2 Division of Psychosocial Medicine, National Jewish Health, Denver, Colorado, USA 3 ...
thorax.bmj3d
Case finding for chronic obstructive pulmonary disease: a model for optimising a targeted approach
Objectives Case finding is proposed as an important component of the forthcoming English National Clinical Strategy for chronic obstructive pulmonary disease (COPD) because of accepted widespread ...
thorax.bmj5d
Matrix metalloproteinases in destructive pulmonary pathology
Correspondence to: Dr P T G Elkington Department of Infectious Diseases, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK; p.elkington{at}imperial.ac.uk Matrix ...
thorax.bmj9d
Prospective study of the incidence, aetiology and outcome of adult lower respiratory tract illness in the community
BACKGROUND Acute lower respiratory tract illness in previously well adults is usually labelled as acute bronchitis and treated with antibiotics without establishing the aetiology. Viral infection is ...
thorax.bmj8d
Association between vitamin D status at 3 years and eosinophilic asthma in 6-year-old children with a history of severe bronchiolitis
The association between early childhood serum 25-hydroxyvitamin D (25(OH)D) and eosinophilic asthma remains unclear. We investigated this association using multicentre prospective data from 584 ...