The majority (79%) of cardiac amyloidosis cases were responsible for sudden cardiac death. Cardiac amyloidosis can be associated with sudden cardiac death and is often undiagnosed during a person’s ...

Large v-waves with an amplitude of 10 mm Hg or more were a determinant of all-cause mortality and rehospitalization due to heart failure events in patients with wild-type ATTR-CM. Elevated v-wave ...

The recommendations were based on the available evidence, its certainty, and key judgments using the Grading of Recommendations Assessment, Development and Evaluation framework. New guidelines ...

There were 3 unmet needs in CIDP including the lack of specific biomarkers for the disease, weighing the relative value of various metrics, and understanding the optimal timing and approach to assess ...

Patients treated with deep brain stimulation of the centromedian nucleus (CM-DBS) showed improvements in seizure burden and alertness as reported by their caregivers. Deep brain stimulation of the ...

The authors used individual patient data from garadacimab trials (phase 2 and 3 VANGUARD) and published summary data from the phase 3 HELP trial for lanadelumab. Garadacimab may offer superior ...

Intravenous immunoglobulin-induced thrombocytopenia was reported in 146 cases, with the highest incidence seen in patients with immune-mediated skin diseases. Intravenous immunoglobulin (IVIg) therapy ...

The updated 2025 BSR management recommendations for patients with AAV provide systematic and evidence-based recommendations to support UK clinicians in managing AAV across the entire life course.

In addition to a 69.4% CR rate, the team observed good tolerability of the R2-MTX regimen, suggesting its suitability for older or less fit patients. High-dose methotrexate (HD-MTX) with lenalidomide ...

Although treatment was started with rituximab upon the CAD diagnosis, she died within 5 days. A case has been reported of a patient with a history of Raynaud’s phenomenon who was hospitalized due to ...

Among patients with ATTR-CM who underwent catheter ablation, those with stage I amyloidosis had fewer atrial tachyarrhythmia recurrences and better clinical outcomes. Catheter ablation for atrial ...

In CIDP, SOC therapies (immunoglobulins/corticosteroids) are burdensome, have variable efficacy, and significant side-effects. Two phase 3 clinical trials, MOBILIZE ...